This digital artwork is a gross representation of a humanoid skull that has been distorted and turned into a fluid, organic form. The skull is composed primarily of blues, purples, and blacks, which only aid in the sense of liquefaction that the viewer is meant to understand. There is a sense of tension and unease created by the collapse of one eye chamber, the moaning alien jaw, and the overall sharp lines and curves.
The background may suggest drywall mixed with high-velocity goop or Nickelodeon slime. This is thematically relevant for many reasons, which should be obvious to the casual observer.
This one always kinda freaked me out.